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Filgotinib maleate is a selective active JAK1 inhibitor, with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Felgotinib (maleic acid) can be used in the research of rheumatoid arthritis (RA) and Crohn's disease [1] [2].
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